86-7930-97 ［取扱停止］Mouse IL-6 Protein, His Tag 50ug IL6-M5245
特徴
- Background：Interleukin 6 (IL-6) is also known as HGF, BSF2,HSF, IFNB2 and IL-6, originally identified as a B cell differentiation factor, is a multifunctional cytokine that regulates immune responses, hematopoiesis, acute phase responses, and inflammatory reactions.It is secreted by T cells, macrophages , monocytes, fibroblasts,endothelial cells,et.al.
- to stimulate immune response to trauma, especially burns or other tissue damage leading to inflammation.
- Interleukin 6 has been shown to interact with interleukin-6 receptor and glycoprotein.
- IL-6 is relevant to many disease processes such as diabetes,atherosclerosis, depression,Alzheimer's Disease,systemic,lupus erythematosus,prostate cancer and rheumatoid arthritis.
- Advanced/metastatic cancer patients have higher levels of IL-6 in their blood.Hence there is an interest in developing anti-IL-6 agents as therapy against many of these diseases.
仕様
- サイズ：50ug
- Source：Mouse IL-6, His Tag (IL6-M5245) is expressed from human 293 cells (HEK293). It contains AA Phe 25 - Thr 211 (Accession # P08505-1).
- Molecule：IL-6
- Synonyms：IL6,Interleukin-6,BSF2,HSF,IFNB2
- Species：Mouse
- Tag：His Tag
- Expression Systems：HEK293
- Expression Rigeion：Phe 25 - Thr 211
- Conjugate：Unconjugated
- Accession：NP_112445.1
- Molecular Weight：23.6 kDa
- Characteristics：This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 23.6 kDa. The protein migrates as 25-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
- Purity：>90% as determined by SDS-PAGE.
- Buffer：PBS, pH7.4
- Package Size：50ug*1
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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86-7930-96
Mouse IL-6 Protein, His Tag 20ug
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86-7930-97
Mouse IL-6 Protein, His Tag 50ug
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