Background：Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds.
Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport).
IgG1 Fc was reported has a novel role as a potential anti-inflammatory drug for treatment of human autoimmune diseases.
仕様
サイズ：25ug
Source：Biotinylated Mouse IgG1 Fc, Avitag (IG1-M8211) is expressed from human 293 cells (HEK293). It contains AA Val 98 - Lys 324 (Accession # AAK53870.1).
Molecule：IgG1 Fc
Synonyms：IgG1
Species：Mouse
Tag：Avi Tag
Expression Systems：HEK293
Expression Rigeion：Val 98 - Lys 324
Conjugate：Precision Avi
Accession：AAK53870.1
Molecular Weight：27.4 kDa
Characteristics：This protein carries an Avi tag at the C-terminus. The protein has a calculated MW of 27.4 kDa. The protein migrates as 33 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
