Background：ASGPR, a transmembrane C-type lectin, recognizes a wide variety of ligands that contain either terminal galactose (Gal) or N-acetylgalactosamine (GalNAc) residues and has been identified as a highly selective receptor on hepatocytes.
The ASGR is composed of both a major (ASGR1) and minor subunit (ASGR2).
ASGR1 has been shown to be efficiently targeted to the plasma membrane and to undergo constitutive endocytosis and recycling and found mainly expressed in the human liver.
仕様
サイズ：100ug
Source：Human ASGR1, Fc Tag (AS1-H5253) is expressed from human 293 cells (HEK293). It contains AA Gln 62 - Leu 291 (Accession # P07306-1).
Molecule：ASGR1
Synonyms：ASGP-R 1, ASGPR 1, C-type lectin domain family 4 member H1, Hepatic lectin H1, HL-1
Species：Human
Tag：Fc Tag
Expression Systems：HEK293
Expression Rigeion：Gln 62 - Leu 291
Conjugate：Unconjugated
Accession：NP_001662.1
Molecular Weight：52.8 kDa
Characteristics：This protein carries a human IgG1 Fc tag at the N-terminus. The protein has a calculated MW of 52.8 kDa. The protein migrates as 65-75 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
