86-7930-63 ［取扱停止］Human TOP2A / TOP2 Protein, Tag Free 20ug TOA-H5117
特徴
- Background：DNA topoisomerase 2-alpha (TOP2A) is also known as DNA topoisomerase II, alpha isozyme and TOP2.
- It is a topoisomerase which control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands.
- Topoisomerase II makes double-strand breaks.
- Essential during mitosis and meiosis for proper segregation of daughter chromosomes.
- May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation.
- Also it is the targets of anti-cancer drugs that cause treatment-related leukemias with balanced translocations.
仕様
- サイズ：20ug
- Source：Human TOP2A, Tag Free (TOA-H5117) is expressed from E.coli cells. It contains AA Ser 1354 - Ser 1473 (Accession # P11388-1).
- Molecule：TOP2A
- Synonyms：TOP2A,TOP2,DNA topoisomerase 2-alpha,DNA topoisomerase II,alpha isozyme
- Species：Human
- Tag：Tag Free
- Expression Systems：E.coli
- Expression Rigeion：Ser 1354 - Ser 1473
- Conjugate：Unconjugated
- Accession：NP_001058.2
- Molecular Weight：12.8 kDa
- Characteristics：This protein carries no "tag". The protein has a calculated MW of 12.8 kDa. The protein migrates as 20 kDa under reducing (R) condition (SDS-PAGE).
- Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
- Purity：>90% as determined by SDS-PAGE.
- Buffer：50 mM Tris, 0.5 M KCl, pH8.0
- Package Size：20ug*1
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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86-7930-64
Human TOP2A / TOP2 Protein, Tag Free 100ug
|
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86-7930-63
Human TOP2A / TOP2 Protein, Tag Free 20ug
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