86-7930-33 ［取扱停止］Human CD39 Protein, Mouse IgG2a Fc Tag 100ug CD9-H5253
特徴
- Background：CD39 is also known as Ectonucleoside triphosphate diphosphohydrolase 1, ENTPD1, NTPDase 1, Ecto-ATPDase 1, in the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission.
- Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP.
- Hydrolyzes ATP and ADP equally well.
- NTPDase-1 was originally described as CD39, a B lymphocyte cell surface marker, but it is also present on the surface of natural killer cells, T cells, and some endothelial cells.Regulatory T cells(Tregs) mediate immunosuppression through multiple, non-redundant, cell-contact dependent and independent mechanisms, a growing body of evidence suggests an important role for the CD39-CD73-adenosine pathway.
- CD39 ectonucleotidase is the rate-limiting enzyme of a cascade leading to the generation of suppressive adenosine that alters CD4 and CD8 T cell and natural killer cell antitumor activities.
仕様
- サイズ：100ug
- Source：Human CD39, Mouse IgG2a Fc Tag (CD9-H5253) is expressed from human 293 cells (HEK293). It contains AA Thr 38 - Val 478 (Accession # P49961-1).
- Molecule：CD39
- Synonyms：CD39,ENTPD1,NTPDase 1,Entpd1,Ecto-ATPDase 1,Ecto-ATPase 1
- Species：Human
- Tag：Mouse IgG Fc Tag
- Expression Systems：HEK293
- Expression Rigeion：Thr 38 - Val 478
- Conjugate：Unconjugated
- Accession：NP_001767.3
- Molecular Weight：77.3 kDa
- Characteristics：This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 77.3 kDa. The protein migrates as 95-110 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Endotoxin Level：Less than 0.1 EU per ug by the LAL method.
- Purity：>95% as determined by SDS-PAGE.
- Buffer：20 mM Tris, 500 mM Argnine, 150 mM NaCl, pH7.5
- Package Size：100ug*1
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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86-7930-32
Human CD39 Protein, Mouse IgG2a Fc Tag 25ug
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86-7930-33
Human CD39 Protein, Mouse IgG2a Fc Tag 100ug
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