Background：Both Interleukin-2 receptor subunit beta and Interleukin-2 receptor subunit gamma are receptor for interleukin-2.
Common subunit for the receptors for a variety of interleukins.
Interacts with SHB upon interleukin stimulation.
Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15.
This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.
IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit).
The high and intermediate affinity forms also associate with a gamma subunit.
仕様
サイズ：100ug
Source：Human IL-2RB&IL-2RG Heterodimer Protein, Fc Tag&Fc Tag (MALS verified) (ILG-H5254) is expressed from human 293 cells (HEK293). It contains AA Ala 27 - Asp 239 (IL-2RB) & Leu 23 - Asn 254 (IL-2RG) (Accession # P14784-1 (IL-2RB) & P31785-1 (IL-2RG)).
Molecule：IL-2 R beta & IL-2 R gamma
Synonyms：IL-2 R beta & IL-2 R gamma,IL-2RB & IL-2RG
Species：Human
Tag：Fc Tag
Expression Systems：HEK293
Expression Rigeion：Ala 27 - Asp 239 (IL-2RB) & Leu 23 - Asn 254 (IL-2RG)
Molecular Weight：51.1 kDa (IL-2RB) and 53.6 kDa (IL-2RG)
Characteristics：Human IL-2RB&IL-2RG Heterodimer Protein, Fc Tag&Fc Tag is produced by co-expression of IL-2RB and IL-2RG, has a calculated MW of 51.1 kDa (IL-2RB) and 53.6 kDa (IL-2RG). Subunit IL-2RB is fused with a human IgG1 Fc tag at the C-terminus and subunit IL-2RG is fused with a human IgG1 Fc tag at the C-terminus. The reducing (R) protein migrates as 65-80 kDa and 90-100 kDa respectively due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
