86-7930-08 ［取扱停止］Human IL-17F Protein, His Tag 20ug ILF-H5244
特徴
- Background：Interleukin-17F (IL17F) is also known as Interleukin-24 (IL24), Cytokine ML-1, is a secreted disulfide-linked homodimer which belongs to the IL-17 family.
- There are at least six members of the IL-17 family in humans and in mice: IL-17A, IL-17B, IL-17C, IL-17D, IL-17E (also called IL-25) and IL-17F (also called IL-24).
- IL-17 represents a family of structurally related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles.
- IL-17F / IL-24 is expressed in activated, but not resting, CD4+ T-cells and activated monocytes.
- IL17F / Interleukin-24 stimulates the production of other cytokines such as IL-6, IL-8 and granulocyte colony-stimulating factor, and can regulate cartilage matrix turnover.
- IL17F / IL-24 stimulates PBMC and T-cell proliferation and Inhibits angiogenesis.
- Defects in IL17F are the cause of familial candidiasis type 6 (CANDF6).
仕様
- サイズ：20ug
- Source：Human IL-17F, His Tag (ILF-H5244) is expressed from human 293 cells (HEK293). It contains AA Arg 31 - Gln 163 (Accession # Q96PD4-1).
- Molecule：IL-17F
- Synonyms：IL-17F,Interleukin-17F,Cytokine ML-1
- Species：Human
- Tag：His Tag
- Expression Systems：HEK293
- Expression Rigeion：Arg 31 - Gln 163
- Conjugate：Unconjugated
- Accession：NP_443104.1
- Molecular Weight：16.8 kDa
- Characteristics：This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 16.8 kDa. The protein migrates as 22-25 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
- Purity：>95% as determined by SDS-PAGE.
- Buffer：PBS, pH7.4
- Package Size：20ug*1
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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86-7930-09
Human IL-17F Protein, His Tag 50ug
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86-7930-08
Human IL-17F Protein, His Tag 20ug
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