86-7930-01 ［取扱停止］Biotinylated Human / Cynomolgus / Rhesus macaque CD28 Protein, His,Avitag, active dimer (MALS verified) 25ug CD8-H82E5
特徴
- Background：T-cell-specific surface glycoprotein CD28 is also known as TP44, is a single-pass type I membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain.
- is one of the molecules expressed on T cells that provide co-stimulatory signals, which are required for T cell activation.
- CD28 is the receptor for CD80 (B7.1) and CD86 (B7.2).
- When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs).
- The CD86 expression on antigen presenting cells is constitutive.
- CD28 is the only B7 receptor constitutively expressed on naive T cells.
仕様
- サイズ：25ug
- Source：Biotinylated Human / Cynomolgus / Rhesus macaque CD28, His,Avitag (CD8-H82E5) is expressed from human 293 cells (HEK293). It contains AA Asn 19 - Pro 152 (Accession # P10747-1).
- Molecule：CD28
- Synonyms：CD28,Tp44
- Species：Human / Cynomolgus / Rhesus macaque
- Tag：His Tag & Avi Tag
- Expression Systems：HEK293
- Expression Rigeion：Asn 19 - Pro 152
- Conjugate：Precision Avi
- Accession：NP_006130.1
- Molecular Weight：18.7 kDa
- Characteristics：This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag). The protein has a calculated MW of 18.7 kDa. As a result of glycosylation, the protein migrates as 33-45 kDa under reducing (R) condition, and 55-80 kDa under non-reducing (NR) condition (SDS-PAGE).
- Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
- Purity：>90% as determined by SDS-PAGE.
- Buffer：PBS, pH7.4
- Package Size：25ug*1
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