Background：Protein-arginine deiminase type-2 (PADI2) are calcium-dependent histone-modifying enzymes whose activity is dysregulated in inflammatory diseases and cancer.
This enzyme which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions.
The type II enzyme is the most widely expressed family member.
Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages.
仕様
サイズ：50ug
Source：Human PADI2, His Tag (PA2-H5543) is expressed from Baculovirus-Insect cells. It contains AA Met 1 - Pro 665 (Accession # Q9Y2J8-1).
Molecule：PADI2
Synonyms：PADI2,PAD-H19,KIAA0994,PAD2,PDI2
Species：Human
Tag：His Tag
Expression Systems：InsectCells
Expression Rigeion：Met 1 - Pro 665
Conjugate：Unconjugated
Accession：NP_31391.2
Molecular Weight：77.4 kDa
Characteristics：This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 77.4 kDa. The protein migrates as 66-70 kDa under reducing (R) condition (SDS-PAGE).
Endotoxin Level：Less than 0.01 EU per ug by the LAL method.
