Background:siglec-9 (HGMW-approved symbol SIGLEC9) a member of the sialic acid-binding Ig-like lectin (Siglec) family, which belongs to the immunoglobulin superfamily (IgSF).
SIGLEC9 shows a high degree of homology to many members of the siglec family, including siglec-7 (80%), siglec-8 (72%), siglec-5 (65%), and CD33 (64%).
This high degree of homology is also conserved in the extracellular Ig-like domains.
They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by varying numbers of Ig-like C2-type domains。Siglec-9 with a hydrophobic signal peptide, an N-terminal Ig-likeV-type domain, two Ig-like C2-type domains, a transmembrane region and a cytoplasmic tail.
仕様
サイズ:100ug
Source:Cynomolgus Siglec-9, His Tag (SI9-C52H9) is expressed from human 293 cells (HEK293). It contains AA Gln 20 - Gly 350 (Accession # XP_005590140.1).
Molecule:Siglec-9
Synonyms:Siglec-9,SIGLEC9,CDw329,CD329
Species:Cynomolgus
Tag:His Tag
Expression Systems:HEK293
Expression Rigeion:Gln 20 - Gly 350
Conjugate:Unconjugated
Accession:XP_005590140.1
Molecular Weight:38.0 kDa
Characteristics:This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 38.0 kDa. The protein migrates as 55-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level:Less than 1.0 EU per ug by the LAL method.