Background：Interleukin-17 receptor E (IL-17 RE) is an orphan receptor of the IL-17 receptor family, also known as UNQ3056, PRO9877, IL-17 Receptor E.
IL-17RE is known to be expressed in the pancreas, brain, and prostate.
IL-17RE is a receptor specific to IL-17C and has an essential role in host mucosal defense against infection.
IL-17C functioned in a unique autocrine manner, binding to a receptor complex consisting of the receptors IL-17RA and IL-17RE, which was preferentially expressed on tissue epithelial cells.
Some data identify IL-17RE as a receptor of IL-17C that regulates early innate immunity to intestinal pathogens.
仕様
サイズ：100ug
Source：Human IL-17 RE (155-454), Fc Tag (ILE-H5256) is expressed from human 293 cells (HEK293). It contains AA Thr 155 - His 454 (Accession # Q8NFR9-1).
Molecule：IL-17 RE
Synonyms：IL-17 RE,IL17RE,IL-17RE,IL-17 receptor E
Species：Human
Tag：Fc Tag
Expression Systems：HEK293
Expression Rigeion：Thr 155 - His 454
Conjugate：Unconjugated
Accession：NP_705613.1
Molecular Weight：60.5 kDa
Characteristics：This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 60.5 kDa. The protein migrates as 66-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
Purity：>95% as determined by SDS-PAGE.
Buffer：Tris with Glycine, Arginine and NaCl, pH7.5
