Background：AXL Receptor Tyrosine Kinase is also known as Tyrosine-protein kinase receptor UFO, which belongs to the protein kinase superfamily, Tyr protein kinase family and AXL/UFO subfamily.
AXL contains two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains and one protein kinase domain.
AXL is highly expressed in metastatic colon tumors.
AXL is activated by GAS6-binding and subsequent autophosphorylation.
AXL is involved in signal transduction from the extracellular matrix into the cytoplasm by binding growth factors, and thus implicated in the stimulation of cell proliferation.
仕様
サイズ：100ug
Source：Cynomolgus Axl, His Tag (AXL-C52H3) is expressed from human 293 cells (HEK293). It contains AA Pro 27 - Pro 293 (Accession # XP_005589384.2).
Molecule：Axl
Synonyms：AXL,UFO
Species：Cynomolgus
Tag：His Tag
Expression Systems：HEK293
Expression Rigeion：Pro 27 - Pro 293
Conjugate：Unconjugated
Accession：XP_005589384.2
Molecular Weight：30.7 kDa
Characteristics：This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 30.7 kDa. The protein migrates as 42-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
