Background：serum albumin (SA) is also known as ALB, which is the main protein of plasma and has a good binding capacity for water,Ca2+,Na+,K+,fatty acids,hormones, bilirubin and drugs.The main function of SA is the regulation of the colloidal osmotic pressure of blood.
As Major zinc transporter in plasma, SA typically binds about 80% of all plasma zinc.
A variant structure of albumin could lead to increased binding of zinc resulting in an asymptomatic augmentation of zinc concentration in the blood.
Defects in serum albumin can cause familial dysalbuminemic hyperthyroxinemia which is a form of euthyroid hyperthyroxinemia that is due to increased affinity of serum albumin for T4.
It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.
仕様
サイズ：25ug
Source：Biotinylated Cynomolgus Serum Albumin, His,Avitag (CSA-C82E5) is expressed from human 293 cells (HEK293). It contains AA Asp 25 - Ala 608 (Accession # A2V9Z4-1).
Molecule：Serum Albumin
Synonyms：Serum albumin,ALB,Alb
Species：Cynomolgus
Tag：His Tag & Avi Tag
Expression Systems：HEK293
Expression Rigeion：Asp 25 - Ala 608
Conjugate：Precision Avi
Accession：NP_001306284.1
Molecular Weight：69.7 kDa
Characteristics：This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag). The protein has a calculated MW of 69.7 kDa. The protein migrates as 70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
