Background：Frizzled-7 (FZD7) is also known as FzE3, which belongs to the G-protein coupled receptor Fz/Smo family.
Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes.
FZD7 contains one FZ (frizzled) domain.
FZD7 is receptor for Wnt proteins.
FZD7 may be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
FZD7 interacts with MAGI3 and DVL1.
仕様
サイズ：100ug
Source：Human Frizzled-7, His Tag (FZ7-H52H9) is expressed from human 293 cells (HEK293). It contains AA Gln 33 - Leu 185 (Accession # O75084-1).
Molecule：Frizzled-7
Synonyms：FZD7,Frizzled-7,FzE3,Fz-7,hFz7
Species：Human
Tag：His Tag
Expression Systems：HEK293
Expression Rigeion：Gln 33 - Leu 185
Conjugate：Unconjugated
Accession：NP_003498.1
Molecular Weight：18.6 kDa
Characteristics：This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 18.6 kDa. The protein migrates as 25-32 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
