Background：Interleukin-5 receptor subunit alpha (IL5RA) is also known as IL-5 receptor subunit alpha, IL-5R subunit alpha and CD125,which is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and type 5 subfamily.IL5R, a heterodimer of an alpha and a beta subunit, is expressed on eosinophils and basophils.
IL5RA / CD125 is the receptor for interleukin-5 (IL5) and the alpha chain can bind to IL5.
The WSXWS motif of IL5RA appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.The beta subunit of IL5R is common to the IL3, IL5 and GM-CSF receptors.
仕様
サイズ：50ug
Source：Human IL-5 R alpha, Fc Tag (ILA-H5259) is expressed from human 293 cells (HEK293). It contains AA Asp 21 - Trp 342 (Accession # Q01344-1).
Molecule：IL-5 R alpha
Synonyms：IL5Ra,CD125
Species：Human
Tag：Fc Tag
Expression Systems：HEK293
Expression Rigeion：Asp 21 - Trp 342
Conjugate：Unconjugated
Accession：NP_000555.2
Molecular Weight：63.2 kDa
Characteristics：This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 63.2 kDa. The protein migrates as 70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
