Background:CD94(Natural killer cells antigen CD94) is also known as KLRD1, KP43, NK cell receptor, Killer cell lectin-like receptor subfamily D member 1.
CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.
KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus.
CD94 pairs with the NKG2 molecule as a heterodimer.
The CD94/NKG2 complex, on the surface of natural killer cells interacts with Human Leukocyte Antigen (HLA)-E on target cells.
仕様
サイズ:100ug
Source:Human CD94, Mouse IgG2a Fc Tag (CD4-H5253) is expressed from human 293 cells (HEK293). It contains AA Lys 32 - Ile 179 (Accession # Q13241-1).
Molecule:CD94
Synonyms:CD94,KLRD1,KP43,NK cell receptor
Species:Human
Tag:Mouse IgG Fc Tag
Expression Systems:HEK293
Expression Rigeion:Lys 32 - Ile 179
Conjugate:Unconjugated
Molecular Weight:44.0 kDa
Characteristics:This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 44.0 kDa. The protein migrates as 50-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level:Less than 0.1 EU per ug by the LAL method.
Purity:>95% as determined by SDS-PAGE.
Buffer:Tris with Glycine, Arginine and NaCl, pH7.5