Background：Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily.
GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death.
GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.
仕様
サイズ：100ug
Source：Canine GITR, His Tag (GIR-C52H6) is expressed from human 293 cells (HEK293). It contains AA Gly 23 - Pro 154 (Accession # D7F619-1).
Molecule：GITR
Synonyms：AITR,GITR,TNFRSF18,CD357
Species：Canine
Tag：His Tag
Expression Systems：HEK293
Expression Rigeion：Gly 23 - Pro 154
Conjugate：Unconjugated
Accession：NP_001177673.1
Molecular Weight：15.8 kDa
Characteristics：This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 15.8 kDa. The protein migrates as 20-25 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
