86-7928-50 ［取扱停止］Mouse CD73 / NT5E Protein, His Tag (active enzyme) 20ug CD3-M52H9
特徴
- Background：5'-nucleotidase (5'-NT), also known as ecto-5'-nucleotidase or CD73 (cluster of differentiation 73), is an enzyme that is encoded by the NT5E gene.
- CD73 commonly serves to convert AMP to adenosine.
- Ecto-5-prime-nucleotidase (5-prime-ribonucleotide phosphohydrolase) catalyzes the conversion at neutral pH of purine 5-prime mononucleotides to nucleosides, the preferred substrate being AMP.
- Other forms of 5-prime nucleotidase exist in the cytoplasm and lysosomes and can be distinguished from ecto-NT5 by their substrate affinities, requirement for divalent magnesium ion, activation by ATP, and inhibition by inorganic phosphate.
- Rare allelic variants are associated with a syndrome of adult-onset calcification of joints and arteries (CALJA) affecting the iliac, femoral, and tibial arteries reducing circulation in the legs and the joints of the hands and feet causing pain.
仕様
- サイズ：20ug
- Source：Mouse CD73, His Tag (CD3-M52H9) is expressed from human 293 cells (HEK293). It contains AA Trp 29 - Ser 551 (Accession # Q61503-1).
- Molecule：CD73
- Synonyms：CD73,NT5E,5'-Nucleotidase,5'-NT,NT5,NTE
- Species：Mouse
- Tag：His Tag
- Expression Systems：HEK293
- Expression Rigeion：Trp 29 - Ser 551
- Conjugate：Unconjugated
- Accession：NP_035981
- Molecular Weight：59.9 kDa
- Characteristics：This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 59.9 kDa. The protein migrates as 66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
- Purity：>90% as determined by SDS-PAGE.
- Buffer：20 mM Tris, 120 mM NaCl, pH7.5
- Package Size：20ug*1
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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86-7928-50
Mouse CD73 / NT5E Protein, His Tag (active enzyme) 20ug
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86-7928-51
Mouse CD73 / NT5E Protein, His Tag (active enzyme) 100ug
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