Background：The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands.
The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4).
Mutations affecting EGFR expression or activity could result in cancer.
仕様
サイズ：100ug
Source：Rhesus macaque EGF R, Fc Tag (EGR-C5252) is expressed from human 293 cells (HEK293). It contains AA Leu 25 - Ser 645 (Accession # P55245).
Molecule：EGF R
Synonyms：EGFR,ERBB,ERBB1,HER1,PIG61,mENA
Species：Rhesus macaque
Tag：Fc Tag
Expression Systems：HEK293
Expression Rigeion：Leu 25 - Ser 645
Conjugate：Unconjugated
Molecular Weight：95.3 kDa
Characteristics：This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 95.3 kDa. The protein migrates as 116-120 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
Purity：>95% as determined by SDS-PAGE.
Buffer：Tris with Glycine, Arginine and NaCl, pH7.5
