Background：T-cell surface glycoprotein CD4 is also known as T-cell surface antigen T4/Leu-3.
CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain.
CD4 is accessory protein for MHC class-II antigen/T-cell receptor interaction.
CD4 induces the aggregation of lipid rafts.
CD4 is a primary receptor used by HIV-1 to gain entry into host T cells.
HIV infection leads to a progressive reduction of the number of T cells possessing CD4 receptors.
Therefore, medical professionals refer to the CD4 count to decide when to begin treatment for HIV-infected patients.
仕様
サイズ：100ug
Source：Rhesus macaque CD4, His Tag (CD4-C52H7) is expressed from human 293 cells (HEK293). It contains AA Lys 26 - Trp 390 (Accession # G7N5T8).
Molecule：CD4
Synonyms：CD4,CD4mut,LEU3
Species：Rhesus macaque
Tag：His Tag
Expression Systems：HEK293
Expression Rigeion：Lys 26 - Trp 390
Conjugate：Unconjugated
Molecular Weight：42.3 kDa
Characteristics：This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 42.3 kDa. The protein migrates as 50-57 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
