Background：Transferrin receptor protein 2 (TFR2) is a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain.
The mutations in TFR2 gene have been associated with hereditary hemochromatosis type III.
Furthermore, TFR2 is involved in the uptake of transferrin-bound iron into cells by endocytosis, although its role is minor compared to transferrin receptor 1.
仕様
サイズ：50ug
Source：Mouse TFR2, Mouse Fc Tag (TF2-M5269) is expressed from human 293 cells (HEK293). It contains AA Arg 103 - Phe 798 (Accession # Q9JKX3-1).
Molecule：Transferrin R2
Synonyms：Transferrin R2,TFR2
Species：Mouse
Tag：Mouse IgG Fc Tag
Expression Systems：HEK293
Expression Rigeion：Arg 103 - Phe 798
Conjugate：Unconjugated
Accession：NP_056614.3
Molecular Weight：101.1 kDa
Characteristics：This protein carries a mouse IgG1 Fc tag at the N-terminus. The protein has a calculated MW of 101.1 kDa. The protein migrates as 116 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 0.1 EU per ug by the LAL method.
Purity：>95% as determined by SDS-PAGE.
Buffer：Tris with Glycine, Arginine and NaCl, pH7.5
