Background：Tumor necrosis factor ligand superfamily member 9 (4-1BBL) is also known as 4-1BB ligand, CD137L or TNFSF9, which is a cytokine that binds to TNFRSF9.
4-1BBL is the high affinity ligand of 4-1BB.
4-1BBL induces the proliferation of activated peripheral blood T-cells.
Also, 4-1BBL may have a role in activation-induced cell death (AICD).
Furthermore, 4-1BBL may play a role in cognate interactions between T-cells and B-cells/macrophages.
As for diseases, 4-1BBL is involved in cancers, infectious diseases and autoimmune diseases.
仕様
サイズ：50ug
Source：Mouse 4-1BB Ligand, Fc Tag (41L-M5257) is expressed from human 293 cells (HEK293). It contains AA Arg 104 - Glu 309 (Accession # NP_033430).
Molecule：4-1BB Ligand
Synonyms：4-1BB Ligand,TNFSF9,CD137L
Species：Mouse
Tag：Fc Tag
Expression Systems：HEK293
Expression Rigeion：Arg 104 - Glu 309
Conjugate：Unconjugated
Accession：NP_033430
Molecular Weight：49.0 kDa
Characteristics：This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 49.0 kDa. The protein migrates as 64-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
Purity：>95% as determined by SDS-PAGE.
Buffer：Tris with Glycine, Arginine and NaCl, pH7.5
