Background：Tumor necrosis factor ligand superfamily member 9 (4-1BBL) is also known as 4-1BB ligand, CD137L or TNFSF9, which is a cytokine that binds to TNFRSF9.
4-1BBL is the high affinity ligand of 4-1BB.
4-1BBL induces the proliferation of activated peripheral blood T-cells.
Also, 4-1BBL may have a role in activation-induced cell death (AICD).
Furthermore, 4-1BBL may play a role in cognate interactions between T-cells and B-cells/macrophages.
As for diseases, 4-1BBL is involved in cancers, infectious diseases and autoimmune diseases.
仕様
サイズ：100ug
Source：Human 4-1BB Ligand, Mouse IgG2a Fc Tag, low endotoxin (41L-H5254) is expressed from human 293 cells (HEK293). It contains AA Ala 50 - Glu 254 (Accession # P41273-1).
Molecule：4-1BB Ligand
Synonyms：4-1BB Ligand,TNFSF9,CD137L
Species：Human
Tag：Mouse IgG Fc Tag
Expression Systems：HEK293
Expression Rigeion：Ala 50 - Glu 254
Conjugate：Unconjugated
Accession：NP_003802.1
Molecular Weight：48.3 kDa
Characteristics：This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 48.3 kDa. The protein migrates as 47-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 0.1 EU per ug by the LAL method.
Purity：>90% as determined by SDS-PAGE.
Buffer：Tris with Glycine, Arginine and NaCl, pH7.5
