Background：Human Integrin alpha 8 beta 1 Heterodimer Protein consists of ITGA8 and ITGB1.
The integrin alpha 8 subunit, isolated by low stringency hybridization, is a novel integrin subunit that associates with beta 1.
The recently identified alpha 8 integrin subunit associates with beta 1 and is predominantly expressed in smooth muscle and other contractile cells in adult tissues, and in mesenchymal and neural cells during development.
In addition, Integrin alpha 8 beta 1 is a receptor for fibronectin and can promote attachment, cell spreading, and neurite outgrowth on fibronectin.
仕様
サイズ：100ug
Source：Human ITGA8&ITGB1 Heterodimer Protein, His Tag&Tag Free (IT1-H52W9) is expressed from human 293 cells (HEK293). It contains AA Phe 39 - Leu 1012 (ITGA8) & Gln 21 - Asp 728 (ITGB1) (Accession # P53708-1 (ITGA8) & P05556-1 (ITGB1)).
Molecule：Integrin alpha 8 beta 1
Synonyms：Integrin alpha 8 beta 1,ITGA8&ITGB1
Species：Human
Tag：His Tag
Expression Systems：HEK293
Expression Rigeion：Phe 39 - Leu 1012 (ITGA8) & Gln 21 - Asp 728 (ITGB1)
Characteristics：Human ITGA8&ITGB1 Heterodimer Protein, His Tag&Tag Free, produced by co-expression of ITGA8 and ITGB1, has a calculated MW of 114.6 kDa (ITGA8) and 83.7 kDa (ITGB1). Subunit ITGA8 is fused with an acidic tail at the C-terminus and followed by a polyhistidine tag and subunit ITGB1 contains no tag but a basic tail at the C-terminus. The non-reducing (NR) protein migrates as 140-170 kDa (ITGA8) and 100-115 kDa (ITGB1) respectively due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
