Background：The colony stimulating factor 1 (CSF1), also known as macrophage colony-stimulating factor (M-CSF), is a secreted cytokine which influences hematopoietic stem cells to differentiate into macrophages or other related cell types.
Eukaryotic cells also produce M-CSF in order to combat intercellular viral infection.
It is one of the three experimentally described colony-stimulating factors.
M-CSF binds to the colony stimulating factor 1 receptor.
Macrophage colony-stimulating factor has been shown to interact with PIK3R2.
M-CSF (or CSF-1) is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival of monocytes, macrophages, and bone marrow progenitor cells.
Locally produced M-CSF in the vessel wall contributes to the development and progression of atherosclerosis.
仕様
サイズ：50ug
Source：Human M-CSF, His Tag (MCF-H5247) is expressed from human 293 cells (HEK293). It contains AA Glu 33 - Arg 255 (Accession # P09603-1).
Molecule：M-CSF
Synonyms：M-CSF,CSF-1,Lanimostim
Species：Human
Tag：His Tag
Expression Systems：HEK293
Expression Rigeion：Glu 33 - Arg 255
Conjugate：Unconjugated
Accession：AAH21117.1
Molecular Weight：26.0 kDa
Characteristics：This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 26.0 kDa. The protein migrates as 36-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
