86-7925-99 ［取扱停止］Human CD73 / NT5E Protein, His Tag (HPLC-verified) (active enzyme) 100ug CD3-H52H7
特徴
- Background：5'-nucleotidase (5'-NT), also known as ecto-5'-nucleotidase or CD73 (cluster of differentiation 73), is an enzyme that is encoded by the NT5E gene.
- CD73 commonly serves to convert AMP to adenosine.
- Ecto-5-prime-nucleotidase (5-prime-ribonucleotide phosphohydrolase) catalyzes the conversion at neutral pH of purine 5-prime mononucleotides to nucleosides, the preferred substrate being AMP.
- Other forms of 5-prime nucleotidase exist in the cytoplasm and lysosomes and can be distinguished from ecto-NT5 by their substrate affinities, requirement for divalent magnesium ion, activation by ATP, and inhibition by inorganic phosphate.
- Rare allelic variants are associated with a syndrome of adult-onset calcification of joints and arteries (CALJA) affecting the iliac, femoral, and tibial arteries reducing circulation in the legs and the joints of the hands and feet causing pain.
仕様
- サイズ：100ug
- Source：Human CD73, His Tag (HPLC-verified) (CD3-H52H7) is expressed from human 293 cells (HEK293). It contains AA Trp 27 - Ser 549 (Accession # P21589-1).
- Molecule：CD73
- Synonyms：CD73,NT5E,5'-Nucleotidase,5'-NT,NT5,NTE
- Species：Human
- Tag：His Tag
- Expression Systems：HEK293
- Expression Rigeion：Trp 27 - Ser 549
- Conjugate：Unconjugated
- Accession：NP_002517.1
- Molecular Weight：59.9 kDa
- Characteristics：This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 59.9 kDa. The protein migrates as 40 kDa and 65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
- Purity：>90% as determined by SDS-PAGE.
- Buffer：20 mM Tris, 120 mM NaCl, pH7.5
- Package Size：100ug*1
- この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）
- 【試薬に関するお問合せ】
- アズワン株式会社 試薬・プロセス材料グループ
- TEL：06-6447-8641
- FAX：06-6447-8642
- E-mail：[email protected]
商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
|
86-7925-98
Human CD73 / NT5E Protein, His Tag (HPLC-verified) (active enzyme) 20ug
|
|
|
86-7925-99
Human CD73 / NT5E Protein, His Tag (HPLC-verified) (active enzyme) 100ug
|
よくあるご質問（FAQ）
掲載カタログ情報
| 掲載カタログ名 | 掲載ページ |
|---|