86-7925-82 ［取扱停止］Biotinylated Human / Cynomolgus / Rhesus macaque CD28 Protein, Fc,Avitag, active dimer (MALS verified) 200ug CD8-H82F2
特徴
- Background：T-cell-specific surface glycoprotein CD28 is also known as TP44, is a single-pass type I membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain.
- is one of the molecules expressed on T cells that provide co-stimulatory signals, which are required for T cell activation.
- CD28 is the receptor for CD80 (B7.1) and CD86 (B7.2).
- When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs).
- The CD86 expression on antigen presenting cells is constitutive.
- CD28 is the only B7 receptor constitutively expressed on naive T cells.
仕様
- サイズ：200ug
- Source：Biotinylated Human / Cynomolgus / Rhesus macaque CD28, Fc,Avitag (CD8-H82F2) is expressed from human 293 cells (HEK293). It contains AA Asn 19 - Pro 152 (Accession # AAH93698). In the region Asn 19 - Pro 152, the AA sequence of Human, Cynomolgus and Rhesus macaque CD28 are homologus.
- Molecule：CD28
- Synonyms：CD28,Tp44
- Species：Human / Cynomolgus / Rhesus macaque
- Tag：Fc Tag & Avi Tag
- Expression Systems：HEK293
- Expression Rigeion：Asn 19 - Pro 152
- Conjugate：Precision Avi
- Accession：AAH93698
- Molecular Weight：43.6 kDa
- Characteristics：This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag). The protein has a calculated MW of 43.6 kDa. As a result of glycosylation, the protein migrates as 55-70 kDa under reducing (R) condition, and 110-130 kDa under non-reducing (NR) condition (SDS-PAGE).
- Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
- Purity：>95% as determined by SDS-PAGE.
- Buffer：Tris with Glycine, Arginine and NaCl, pH7.5
- Package Size：200ug*1
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