Background：Cholera enterotoxin subunit B (CTXB) is also known as cholera enterotoxin B chain, cholera enterotoxin gamma chain and choleragenoid.
Vibrio cholerae O1 exists as two major serotypes, Inaba and Ogawa, which are associated with the O antigen of the lipopolysaccharide and are capable of unequal reciprocal interconversion.
The B subunit pentameric ring directs the A subunit to its target by binding to the GM1 gangliosides present on the surface of the intestinal epithelial cells.
CTXB can bind five GM1 gangliosides.
Also, it has no toxic activity by itself.
仕様
サイズ：50ug
Source：Vibrio cholerae serotype O1 CTXB, His Tag (CTB-V52E8) is expressed from human 293 cells (HEK293). It contains AA Thr 22 - Asn 124 (Accession # P01556).
Molecule：CTXB
Synonyms：CTXB,TOXB
Species：Vibrio cholerae serotype O1
Tag：His Tag
Expression Systems：HEK293
Expression Rigeion：Thr 22 - Asn 124
Conjugate：Unconjugated
Molecular Weight：13.5 kDa
Characteristics：This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 13.5 kDa. The protein migrates as 18-22 kDa under reducing (R) condition (SDS-PAGE).
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
