86-7925-52 ［取扱停止］Human Transthyretin / Prealbumin Protein, His Tag 100ug TTR-H5223
特徴
Background：Transthyretin (TTR) is also known as Prealbumin, ATTR, TBPA, PALB, which belongs to the transthyretin family.
Transthyretin / TTR is a serum and cerebrospinal fluid carrier of the thyroid hormone thyroxine (T4) and retinol-binding protein bound to retinol.
In cerebrospinal fluid TTR is the primary carrier of T4.
TTR also acts as a carrier of retinol (vitamin A) through its association with retinol-binding protein (RBP) in the blood and the CSF.
Less than 1% of TTR's T4 binding sites are occupied in blood.
TTR misfolding and aggregation is known to be associated with the amyloid diseases.
仕様
サイズ：100ug
Source：Human Transthyretin, His Tag (TTR-H5223) is expressed from human 293 cells (HEK293). It contains AA Gly 21 - Glu 147 (Accession # NP_000362).
Molecule：Transthyretin
Synonyms：Transthyretin,TTR,Prealbumin,TBPA,ATTR,PALB,CTS,CTS1,HsT2651
Species：Human
Tag：His Tag
Expression Systems：HEK293
Expression Rigeion：Gly 21 - Glu 147
Conjugate：Unconjugated
Accession：NP_000362
Molecular Weight：14.9 kDa
Characteristics：This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 14.9 kDa. The protein migrates as 17 kDa and 33 kDa under reducing (R) condition (SDS-PAGE) due to the monomer and dimer respectively.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
Purity：>95% as determined by SDS-PAGE.
Buffer：PBS, pH7.4
Package Size：100ug*1
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