Background：Lymphotoxin-beta receptor (LTBR) is also known as Tumor necrosis factor receptor superfamily member 3 (TNFRSF3), Tumor necrosis factor receptor type III (TNF-RIII), which is a single-pass type I membrane protein containing four TNFR-Cys repeat regions.
Except for interacting with HCV core protein, LTBR can not only associate with itself, but also can associate with TRAF3, TRAF4 and TRAF5.
As the receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT, LTBR promotes apoptosis via TRAF3 and TRAF5.
Furthermore, LTBR may play a role in the development of lymphoid organs.
仕様
サイズ：100ug
Source：Human LTBR, Fc Tag (LTR-H5251) is expressed from human 293 cells (HEK293). It contains AA Gln 31 - Met 227 (Accession # P36941-1).
Molecule：LTBR
Synonyms：LTBR,D12S370,TNFCR,TNFR3,TNFRSF3,TNFRIII
Species：Human
Tag：Fc Tag
Expression Systems：HEK293
Expression Rigeion：Gln 31 - Met 227
Conjugate：Unconjugated
Accession：NP_002333
Molecular Weight：48.4 kDa
Characteristics：This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 48.4 kDa. The protein migrates as 55-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
Purity：>95% as determined by SDS-PAGE.
Buffer：Tris with Glycine, Arginine and NaCl, pH7.5
