Background:Interleukin-7 receptor subunit alpha (IL7Ra) is also known as CD antigen CD127, which belongs to the type I cytokine receptor family and type 4 subfamily.
IL7Ra /CD127 is expressed on various cell types, including naive and memory T cells and many others.
IL7Ra /CD127 is receptor for interleukin-7 and also acts as a receptor for thymic stromal lymphopoietin (TSLP).
The IL7 receptor is a heterodimer of IL7R and IL2RG.
The TSLP receptor is a heterodimer of CRLF2 and IL7R.
仕様
サイズ:100ug
Source:Human IL-7 R alpha, Fc Tag (ILA-H5258) is expressed from human 293 cells (HEK293). It contains AA Glu 21 - Gly 236 (Accession # P16871-1).
Molecule:IL-7 R alpha
Synonyms:IL7Ra,CD127
Species:Human
Tag:Fc Tag
Expression Systems:HEK293
Expression Rigeion:Glu 21 - Gly 236
Conjugate:Unconjugated
Accession:NP_002176
Molecular Weight:51.0 kDa
Characteristics:This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 51.0 kDa. The protein migrates as 66-95 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level:Less than 1.0 EU per ug by the LAL method.
Purity:>95% as determined by SDS-PAGE.
Buffer:Tris with Glycine, Arginine and NaCl, pH7.5