Background：Interleukin-27 receptor subunit alpha ( IL27RA) is also known as Cytokine receptor WSX-1, Cytokine receptor-like 1, Type I T-cell cytokine receptor (TCCR), ZcytoR1, IL27RA belongs to the type I cytokine receptor family and type 2 subfamily.
IL27RA contains three fibronectin type-III domains.
IL27RA is highly expressed in lymphoid tissues such as spleen, lymph nodes and peripheral blood leukocytes.
IL27RA is receptor for IL27, but requires IL6ST/gp130 to mediate signal transduction in response to IL27.
IL27RA involved in the regulation of Th1-type immune responses.
IL27RA also appears to be involved in innate defense mechanisms.
仕様
サイズ：100ug
Source：Human IL-27 Ra, Fc Tag (ILA-H5254) is expressed from human 293 cells (HEK293). It contains AA Gln 33 - Arg 514 (Accession # AAH28003).
Molecule：IL-27 Ra
Synonyms：IL27RA,CRL1,TCCR,WSX1
Species：Human
Tag：Fc Tag
Expression Systems：HEK293
Expression Rigeion：Gln 33 - Arg 514
Conjugate：Unconjugated
Accession：AAH28003
Molecular Weight：78.7 kDa
Characteristics：This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 78.7 kDa. The protein migrates as 100-116 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
Purity：>95% as determined by SDS-PAGE.
Buffer：50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
