Background：Interleukin 1 receptor-like 1 (IL1RL1) is also known as ST2, DER4, FIT-1, IL33R, ST2L, ST2V, which belongs to the interleukin-1 receptor family.
IL1RL1 contains three Ig-like C2-type (immunoglobulin-like) domains and one TIR domain.
IL1RL1 is receptor for interleukin-33 (IL-33), its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8.
IL1RL1 possibly involved in helper T-cell function.
IL1RL1 can interact with MYD88, IRAK1, IRAK4, and TRAF6.
仕様
サイズ：200ug
Source：Human IL-1RL1, His Tag (IL1-H5229) is expressed from human 293 cells (HEK293). It contains AA Lys 19 - Phe 328 (Accession # Q01638-2).
Molecule：IL-1RL1
Synonyms：IL1RL1,DER4,FIT-1,IL33R,ST2,ST2L,ST2V,T1
Species：Human
Tag：His Tag
Expression Systems：HEK293
Expression Rigeion：Lys 19 - Phe 328
Conjugate：Unconjugated
Accession：NP_003847.2
Molecular Weight：36.9 kDa
Characteristics：This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 36.9 kDa. The protein migrates as 48-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
