86-7924-69 ［取扱停止］Human IL-18BP Protein, Fc Tag (MALS verified) 200ug ILP-H5253
特徴
- Background：Interleukin-18-binding protein (IL18BP) is also known as Tadekinig-alfa, IL18BPa, which functions as an IL18 inhibitor.
- IL18BP is a secreted protein which contains one Ig-like C2-type (immunoglobulin-like) domain.
- IL18BP does not have a transmembrane domain and hence is not anchored to the cell membrane.
- IL18BP is strongly expressed in heart, lung, placenta and spleen.
- Isoform A of IL18BP binds to IL-18 and inhibits its activity.
- IL18BP also functions as an inhibitor of the early TH1 cytokine response.
- IL18BP suppresses the production of IFN-gamma resulting in reduced T-helper type 1 immune responses.
仕様
- サイズ：200ug
- Source：Human IL-18BP, Fc Tag (ILP-H5253) is expressed from human 293 cells (HEK293). It contains AA Thr 31 - Gly 194 (Accession # NP_001138529).
- Molecule：IL-18BP
- Synonyms：IL18BP,IL18BPa,Tadekinig-alfa
- Species：Human
- Tag：Fc Tag
- Expression Systems：HEK293
- Expression Rigeion：Thr 31 - Gly 194
- Conjugate：Unconjugated
- Accession：NP_001138529
- Molecular Weight：44.3 kDa
- Characteristics：This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 44.3 kDa. The protein migrates as 56-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
- Purity：>95% as determined by SDS-PAGE.
- Buffer：Tris with Glycine, Arginine and NaCl, pH7.5
- Package Size：200ug*1
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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86-7924-68
Human IL-18BP Protein, Fc Tag (MALS verified) 1mg
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86-7924-69
Human IL-18BP Protein, Fc Tag (MALS verified) 200ug
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