86-7924-67 ［取扱停止］Human IL-18BP Protein, His Tag (MALS verified) 200ug ILP-H5222
特徴
- Background：Interleukin-18-binding protein (IL18BP) is also known as Tadekinig-alfa, IL18BPa, which functions as an IL18 inhibitor.
- IL18BP is a secreted protein which contains one Ig-like C2-type (immunoglobulin-like) domain.
- IL18BP does not have a transmembrane domain and hence is not anchored to the cell membrane.
- IL18BP is strongly expressed in heart, lung, placenta and spleen.
- Isoform A of IL18BP binds to IL-18 and inhibits its activity.
- IL18BP also functions as an inhibitor of the early TH1 cytokine response.
- IL18BP suppresses the production of IFN-gamma resulting in reduced T-helper type 1 immune responses.
仕様
- サイズ：200ug
- Source：Human IL-18BP, His Tag (ILP-H5222) is expressed from human 293 cells (HEK293). It contains AA Thr 31 - Gly 194 (Accession # NP_001138529).
- Molecule：IL-18BP
- Synonyms：IL18BP,IL18BPa,Tadekinig-alfa
- Species：Human
- Tag：His Tag
- Expression Systems：HEK293
- Expression Rigeion：Thr 31 - Gly 194
- Conjugate：Unconjugated
- Accession：NP_001138529
- Molecular Weight：18.5 kDa
- Characteristics：This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 18.5 kDa. The protein migrates as 32-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
- Purity：>90% as determined by SDS-PAGE.
- Buffer：PBS, pH7.4
- Package Size：200ug*1
- この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）
- 【試薬に関するお問合せ】
- アズワン株式会社 試薬・プロセス材料グループ
- TEL：06-6447-8641
- FAX：06-6447-8642
- E-mail：[email protected]
商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
|
86-7924-67
Human IL-18BP Protein, His Tag (MALS verified) 200ug
|
|
|
86-7924-66
Human IL-18BP Protein, His Tag (MALS verified) 1mg
|
よくあるご質問（FAQ）
掲載カタログ情報
| 掲載カタログ名 | 掲載ページ |
|---|