86-7924-60 ［取扱停止］Human IL-17E / IL-25 Protein, His Tag 50ug IL5-H4221
特徴
- Background：Interleukin 25 (IL25) is also known as Interleukin-17E (IL-17E), is a distinct member of the IL17 cytokine family comprised of at least six members sharing a conserved cysteine-knot structure but divergent at the N-terminus.
- IL-25 is secreted by type 2 helper T cells (Th2) and mast cells.
- IL25 can induce NF-κB activation, and stimulate the production of IL8.
- Both this cytokine and IL17B are ligands for the cytokine receptor IL17RB.
- IL-25 induces the production of other cytokines, including IL-4, IL-5 and IL-13 in multiple tissues, which stimulate the expansion of eosinophils.
- This cytokine is an important molecule controlling immunity of the gut and has been implicated in chronic inflammation associated with the gastrointestinal tract.
- IL-25 can kill some types of breast cancer cells.
仕様
- サイズ：50ug
- Source：Human IL-17E, His Tag (IL5-H4221) is expressed from human 293 cells (HEK293). It contains AA Tyr 33 - Gly 177 (Accession # NP_073626.1).
- Molecule：IL-17E
- Synonyms：IL-17E,IL-25,Interleukin-25
- Species：Human
- Tag：His Tag
- Expression Systems：HEK293
- Expression Rigeion：Tyr 33 - Gly 177
- Conjugate：Unconjugated
- Accession：NP_073626.1
- Molecular Weight：17.6 kDa
- Characteristics：This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 17.6 kDa. The protein migrates as 23-28 kDa under reducing (R) condition (SDS-PAGE) due to different glycosylation.
- Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
- Purity：>95% as determined by SDS-PAGE.
- Buffer：PBS, pH7.4
- Package Size：50ug*1
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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86-7924-60
Human IL-17E / IL-25 Protein, His Tag 50ug
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86-7924-61
Human IL-17E / IL-25 Protein, His Tag 20ug
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