86-7924-59 ［取扱停止］Human IL-17 RA / CD217 Protein, Fc Tag (MALS verified) 200ug ILA-H5257
特徴
- Background：Interleukin 17 receptor A (IL17RA) is also known as cluster of differentiation w217 (CDw217), is a pro-inflammatory cytokine secreted by activated T-lymphocytes, belong to ubiquitous type I membrane glycoprotein, and binds with low affinity to interleukin 17A (IL17A).
- IL 17R mRNA exhibits a broad tissue distribution, and has been detected in virtually all cells and tissues tested .
- IL 17RA associates with IL 17RC to form a signaling receptor complex for IL 17 and IL 17F .
- Ligand and IL 17RA ligation promotes T cell activation and the production of IL - 6, G-CSF, SCF, and multiple pro-inflammatory chemokines.
- Defects in IL17RA are the cause of familial candidiasis type 5 (CANDF5).
仕様
- サイズ：200ug
- Source：Human IL-17 RA, Fc Tag (MALS verified) (ILA-H5257) is expressed from human 293 cells (HEK293). It contains AA Leu 33 - Trp 320 (Accession # Q96F46-1).
- Molecule：IL-17 RA
- Synonyms：CD217,CDw217,IL-17RA,IL17R,CANDF5,hIL-17R
- Species：Human
- Tag：Fc Tag
- Expression Systems：HEK293
- Expression Rigeion：Leu 33 - Trp 320
- Conjugate：Unconjugated
- Accession：NP_055154.3
- Molecular Weight：60.1 kDa
- Characteristics：This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 60.1 kDa. The protein migrates as 71-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
- Purity：>95% as determined by SDS-PAGE.
- Buffer：Tris with Glycine, Arginine and NaCl, pH7.5
- Package Size：200ug*1
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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86-7924-58
Human IL-17 RA / CD217 Protein, Fc Tag (MALS verified) 1mg
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86-7924-59
Human IL-17 RA / CD217 Protein, Fc Tag (MALS verified) 200ug
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