Background：Interferon alpha/beta receptor 1 ( IFNAR1) is also known as Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1 (CRF2-1), Type I interferon receptor 1, IFNAR, which belongs to the type II cytokine receptor family.
IFNAR1 /IFNAR contains four fibronectin type-III domains.
IFNAR1 associates with IFNAR2 to form the type I interferon receptor.
IFNAR1 is receptor for interferons alpha and beta.
IFNAR1 can transduce IFNB signals without the help of IFNAR2, and not activating the Jak-STAT pathway.
仕様
サイズ：100ug
Source：Human IFNAR1, Fc Tag (IF1-H5253) is expressed from human 293 cells (HEK293). It contains AA Lys 28 - Lys 436 (Accession # NP_000620).
Molecule：IFN-alpha/beta R1
Synonyms：IFNAR1,IFNAR,CRF2-1,IFN-R-1,IFNAR-1
Species：Human
Tag：Fc Tag
Expression Systems：HEK293
Expression Rigeion：Lys 28 - Lys 436
Conjugate：Unconjugated
Accession：NP_000620
Molecular Weight：73.8 kDa
Characteristics：This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 73.8 kDa. The protein migrates as 100-130 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
Purity：>90% as determined by SDS-PAGE.
Buffer：Tris with Glycine, Arginine and NaCl, pH7.5
