86-7923-99 ［取扱停止］Human FGF acidic Protein, Tag Free 200ug AFF-H4116
特徴
- Background：Heparin-binding growth factor 1 is a protein that in humans is encoded by the FGF1 gene.
- The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family.
- FGF acidic is a potent growth factor for fibroblasts and endothelial cells.
- FGF acidic is involved in wound repair, angiogenesis, and development.
- FGF acidic is secreted from cells via an endoplasmic reticulum/Golgi independent mechanism.
- The ability of FGF acidic to bind to heparin sulfate is required for its ability to interact with FGF receptors and induce signaling.
- There are four distinct FGF receptors and each has multiple splice variants.
- FGF acidic binds with high affinity to many, but not all, FGFRs.
- Signaling cascades activated through FGF basic binding to FGFR include the ras-raf-MAPK, PLCγ/PKC, and PI3K/Akt pathways.
仕様
- サイズ：200ug
- Source：Human FGF acidic, Tag Free (AFF-H4116) is expressed from E.coli cells. It contains AA Phe 16 - Asp 155 (Accession # P05230-1).
- Molecule：FGF acidic
- Synonyms：FGF1,AFGF,ECGF,ECGF-beta,ECGFA,ECGFB,FGF-alpha,FGFA,GLIO703,HBGF1
- Species：Human
- Tag：Tag Free
- Expression Systems：E.coli
- Expression Rigeion：Phe 16 - Asp 155
- Conjugate：Unconjugated
- Accession： NP_000791.1
- Molecular Weight：16.0 kDa
- Characteristics：This protein carries no "tag". The protein has a calculated MW of 16.0 kDa. The protein migrates as 16 kDa under reducing (R) condition (SDS-PAGE).
- Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
- Purity：>98% as determined by SDS-PAGE.
- Buffer：PBS, pH7.4
- Package Size：100ug*2
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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86-7923-98
Human FGF acidic Protein, Tag Free 1mg
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86-7923-99
Human FGF acidic Protein, Tag Free 200ug
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