86-7923-69 ［取扱停止］Human DPPIV / CD26 Protein, His Tag (Active dimer) (active enzyme) 50ug DP4-H5221
特徴
- Background：Dipeptidyl peptidase-IV (DPPIV) is also known as adenosine deaminase complexing protein 2, DPPIV or CD26 is antigenic enzyme expressed on the surface of most cell types and is associated with immune regulation, signal transduction and apoptosis.
- It is an intrinsic membrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides.
- The substrates of DPPIV are proline (or alanine)-containing peptides and include growth factors, chemokines, neuropeptides, and vasoactive peptides.
- DPPIV plays a major role in glucose metabolism.
- It is responsible for the degradation of incretins such as GLP-1.
- DPPIV plays an important role in tumor biology, and is useful as a marker for various cancers, with its levels either on the cell surface or in the serum increased in some neoplasms and decreased in others.
- DPPIV also binds the enzyme adenosine deaminase specifically and with high affinity.
- The significance of this interaction has yet to be established.
仕様
- サイズ：50ug
- Source：Human DPPIV, His Tag (DP4-H5221) is expressed from human 293 cells (HEK293). It contains AA Asp 34 - Pro 766 (Accession # NP_001926.2).
- Molecule：DPPIV
- Synonyms：DPP4,ADABP,ADCP2,CD26,DPPIV,TP103
- Species：Human
- Tag：His Tag
- Expression Systems：HEK293
- Expression Rigeion：Asp 34 - Pro 766
- Conjugate：Unconjugated
- Accession：NP_001926.2
- Molecular Weight：85.7 kDa
- Characteristics：This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 85.7 kDa. The protein migrates as 95 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
- Purity：>95% as determined by SDS-PAGE.
- Buffer：PBS, pH7.4
- Package Size：50ug*1
- この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）
- 【試薬に関するお問合せ】
- アズワン株式会社 試薬・プロセス材料グループ
- TEL：06-6447-8641
- FAX：06-6447-8642
- E-mail：[email protected]
商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
|
86-7923-70
Human DPPIV / CD26 Protein, His Tag (Active dimer) (active enzyme) 200ug
|
|
|
86-7923-69
Human DPPIV / CD26 Protein, His Tag (Active dimer) (active enzyme) 50ug
|
よくあるご質問（FAQ）
掲載カタログ情報
| 掲載カタログ名 | 掲載ページ |
|---|