Background：CD Antigen CD27 is also known as Tumor necrosis factor receptor superfamily member 7 (TNFRSF7), which belongs to TNF-receptor superfamily.
CD27 / TNFRSF7 is found in most T-lymphocytes.
CD27 / TNFRSF7 is required for generation and long-term maintenance of T cell immunity.
It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis.
This receptor transduces signals that lead to the activation of NF-κB and MAPK8/JNK.
CD27 has been shown to interact with SIVA1, TRAF2 and TRAF3.
仕様
サイズ：200ug
Source：Human CD27, Fc Tag (CD7-H5254) is expressed from human 293 cells (HEK293). It contains AA Thr 21 - Ile 192 (Accession # NP_001233).
Molecule：CD27
Synonyms：CD27,TNFRSF7,S152,T14,Tp55
Species：Human
Tag：Fc Tag
Expression Systems：HEK293
Expression Rigeion：Thr 21 - Ile 192
Conjugate：Unconjugated
Accession：NP_001233
Molecular Weight：45.9 kDa
Characteristics：This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 45.9 kDa. The protein migrates as 53-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
