Background：Cathepsin S is also known as CTSS, which is a member of the peptidase C1 family.
Cathepsin S is a lysosomal cysteine protease that may participate in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules.
Cathepsin S can function as an elastase over a broad pH range in alveolar macrophages.
The catalytic activity of cathepsin S is similar to cathepsin L, but with much less activity on Z-Phe-Arg-|-NHMec, and more activity on the Z-Val-Val-Arg-|-Xaa compound.
仕様
サイズ：50ug
Source：Human Cathepsin S, His Tag (CTS-H5224) is expressed from human 293 cells (HEK293). It contains AA Gln 17 - Ile 331 (Accession # P25774-1).
Molecule：Cathepsin S
Synonyms：CTSS,Cathepsin S
Species：Human
Tag：His Tag
Expression Systems：HEK293
Expression Rigeion：Gln 17 - Ile 331
Conjugate：Unconjugated
Accession：NP_004070.3
Molecular Weight：24.9 kDa
Characteristics：This protein carries a polyhistidine tag at the C-terminus. This protein undergoes autocatalytic cleavage to release the propeptide and mature chain. The propeptide and mature chain are associated through non‑covalent interactions and with a calculated MW of 36.8 kDa and 24.9 kDa respectively. The protein migrates as 36-42 kDa (propeptide) and 26 kDa (mature) under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
