Background：Cadherin-6 (CDH6) is also known as Kidney cadherin (K-cadherin or KCAD), is a a type II classical cadherin from the cadherin superfamily.
Cadherins are calcium-dependent cell adhesion proteins.
They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
CDH6 / KCAD contains five cadherin domains.
CDH6 is highly expressed in brain, cerebellum, and kidney.
Lung, pancreas, and gastric mucosa show a weak expression and also expressed in certain liver and kidney carcinomas.
仕様
サイズ：100ug
Source：Human Cadherin-6, His Tag (CA6-H5229) is expressed from human 293 cells (HEK293). It contains AA Thr 19 - Ala 615 (Accession # AAH00019).
Molecule：Cadherin-6
Synonyms：CDH6,CAD6,KCAD,K-cadherin,Cadherin-6
Species：Human
Tag：His Tag
Expression Systems：HEK293
Expression Rigeion：Thr 19 - Ala 615
Conjugate：Unconjugated
Accession：AAH00019
Molecular Weight：67.2 kDa & 63.4 kDa
Characteristics：This protein carries a polyhistidine tag at the C-terminus.The Human Cadherin-6 will be further processed into mature form (Ser 54-Ala 615). The protein has a calculated MW of 67.2 kDa (pro-form) and 63.4 kDa (mature-form). The protein migrates as 86-96 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
