Background：Azurocidin (AZU1) is also known as Heparin-binding protein (HBP), Cationic antimicrobial protein CAP37, is a neutrophil granule-derived antibacterial and monocyte- and fibroblast-specific chemotactic glycoprotein.
which belongs to the peptidase S1 family and elastase subfamily.
AZU1 / HBP contains 1 peptidase S1 domain.
AZU1 binds heparin.
The cytotoxic action of AZU1 is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope.
AZU1 may play a role in mediating recruitment of monocytes in the second wave of inflammation.
仕様
サイズ：100ug
Source：Human Azurocidin, His Tag (AZ1-H5225) is expressed from human 293 cells (HEK293). It contains AA Ile 27 - Pro 250 (Accession # AAH69495).
Characteristics：This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 25.0 kDa. The protein migrates as 34-42 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
