86-7923-05 ［取扱停止］Human Axl Protein, His Tag 200ug AXL-H5226
特徴
- Background：AXL Receptor Tyrosine Kinase is also known as Tyrosine-protein kinase receptor UFO, which belongs to the protein kinase superfamily, Tyr protein kinase family and AXL/UFO subfamily.
- AXL contains two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains and one protein kinase domain.
- AXL is highly expressed in metastatic colon tumors.
- AXL is activated by GAS6-binding and subsequent autophosphorylation.
- AXL is involved in signal transduction from the extracellular matrix into the cytoplasm by binding growth factors, and thus implicated in the stimulation of cell proliferation.
仕様
- サイズ：200ug
- Source：Human Axl, His Tag (AXL-H5226) is expressed from human 293 cells (HEK293). It contains AA Ala 26 - Pro 449 (Accession # AAH32229).
- Molecule：Axl
- Synonyms：AXL,UFO
- Species：Human
- Tag：His Tag
- Expression Systems：HEK293
- Expression Rigeion：Ala 26 - Pro 449
- Conjugate：Unconjugated
- Accession：AAH32229
- Molecular Weight：46.6 kDa
- Characteristics：This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 46.6 kDa. The protein migrates as 60-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
- Purity：>95% as determined by SDS-PAGE.
- Buffer：PBS, pH7.4
- Package Size：200ug*1
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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86-7923-04
Human Axl Protein, His Tag 1mg
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86-7923-05
Human Axl Protein, His Tag 200ug
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