Background：Fractalkine is also known as C-X3-C motif chemokine 1 (CX3CL1) and neurotactin.
Fractalkine is a large cytokine protein of 373 amino acids, it contains multiple domains and is the only known member of the CX3C chemokine family.
Fractalkine is found commonly throughout the brain, particularly in neural cells, and its receptor is known to be present on microglial cells.
It has also been found to be essential for microglial cell migration.
CX3CL1 is also up-regulated in the hippocampus during a brief temporal window following spatial learning, the purpose of which may be to regulate glutamate-mediated neurotransmission tone.
This indicates a possible role for the chemokine in the protective plasticity process of synaptic scaling.
仕様
サイズ：25ug
Source：Biotinylated Human CX3CL1, His Tag, primary amine labeling (CX1-H8221) is expressed from human 293 cells (HEK293). It contains AA Gln 25 - Gln 341 (Accession # AAH01163). It is the biotinylated form of Human CX3CL1, His Tag (Cat. No.CX1-H5221).
Molecule：CX3CL1
Synonyms：CX3CL1,Fractalkine
Species：Human
Tag：His Tag
Expression Systems：HEK293
Expression Rigeion：Gln 25 - Gln 341
Conjugate：UltraLys
Accession：AAH01163
Molecular Weight：35.5 kDa
Characteristics：This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 35.5 kDa. The protein migrates as 50-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
