86-7922-48 ［取扱停止］ActiveMax Human LIF Protein, Tag Free 50ug LIF-H521b
特徴
- Background：Leukemia inhibitory factor, or LIF, an interleukin 6 class cytokine, is a protein in cells that affects cell growth and development.Leukemia Inhibitory Factor has several functions such as cholinergic neuron differentiation, control of stem cell pluripotency, bone & fat metabolism, mitogenesis of factor dependent cell lines & promotion of megakaryocyte production in vivo.
- Removal of LIF pushes stem cells toward differentiation, but they retain their proliferative potential or pluripotency.
- Therefore LIF is used in mouse embryonic stem cell culture.
- It is necessary to maintain the stem cells in an undifferentiated state, however genetic manipulation of embryonic stem cells allows for LIF independent growth, notably overexpression of the gene Nanog.
- LIF is not required for culture of human embryonic stem cells.
仕様
- サイズ：50ug
- Source：ActiveMax Human LIF, Tag Free (LIF-H521b) is expressed from human 293 cells (HEK293). It contains AA Ser 23 - Phe 202 (Accession # AAH69540.1).
- Molecule：LIF
- Synonyms：LIF,CDF,DIA,HILDA,MLPLI
- Species：Human
- Tag：Tag Free
- Expression Systems：HEK293
- Expression Rigeion：Ser 23 - Phe 202
- Conjugate：Unconjugated
- Accession：AAH69540.1
- Molecular Weight：19.9 kDa
- Characteristics：This protein carries no "tag". The protein has a calculated MW of 19.9 kDa. The protein migrates as 33-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
- Purity：>90% as determined by SDS-PAGE.
- Buffer：PBS, pH7.4
- Package Size：50ug*1
- この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）
- 【試薬に関するお問合せ】
- アズワン株式会社 試薬・プロセス材料グループ
- TEL：06-6447-8641
- FAX：06-6447-8642
- E-mail：[email protected]
商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
|
86-7922-48
ActiveMax Human LIF Protein, Tag Free 50ug
|
|
|
86-7922-49
ActiveMax Human LIF Protein, Tag Free 20ug
|
よくあるご質問（FAQ）
掲載カタログ情報
| 掲載カタログ名 | 掲載ページ |
|---|