86-7922-45 [取扱停止]ActiveMax Human IL-4 Protein, Tag Free 20ug IL4-H4218
特徴
- Background:Interleukin-4, is a cytokine that induces differentiation of naive helper T cells (Th0 cells to Th2 cells).
- In the presence of IL-4 and IL-13, cytokines that are produced in a Th-2 type response, particularly during allergy and parasitic infections, macrophages become differentially activated, And this cytokine is a ligand for interleukin 4 receptor.
- The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13.
- STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine.
- Recently, researcher found that the cytokine IL-4 plays a key role in development of innate CD8+ T cells in the thymus of several gene-deficient mouse strains, including Itk, KLF2, CBP and Id3, without previous exposure to antigen.
仕様
- サイズ:20ug
- Source:ActiveMax Human IL-4, Tag Free (IL4-H4218) is expressed from human 293 cells (HEK293). It contains AA His 25 - Ser 153 (Accession # P05112-1).
- Molecule:IL-4
- Synonyms:IL4,BCGF1,BSF1
- Species:Human
- Tag:Tag Free
- Expression Systems:HEK293
- Expression Rigeion:His 25 - Ser 153
- Conjugate:Unconjugated
- Accession:AAH67514
- Molecular Weight:15.0 kDa
- Characteristics:This protein carries no "tag". The protein has a calculated MW of 15.0 kDa. The protein migrates as 15 kDa and 19 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Endotoxin Level:Less than 0.1 EU per ug by the LAL method.
- Purity:>90% as determined by SDS-PAGE.
- Buffer:PBS, pH7.4
- Package Size:20ug*1
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
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86-7922-45
ActiveMax Human IL-4 Protein, Tag Free 20ug
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86-7922-44
ActiveMax Human IL-4 Protein, Tag Free 50ug
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