86-7922-35 ［取扱停止］ActiveMax Human Activin A / INHBA Protein, Tag Free, low endotoxin 100ug ACA-H421b
特徴
- Background：Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects.
- Activin enhances FSH biosynthesis and secretion, and participates in the regulation of the menstrual cycle.
- Many other functions have been found to be exerted by activin, including roles in cell proliferation, differentiation, apoptosis, metabolism, homeostasis, immune response, wound repair, and endocrine function.
- Conversely inhibin down regulates FSH synthesis and inhibits FSH secretion.Activins are nonglycosylated homodimers or heterodimers of various β subunits (βA, βB, βC, and βE in mammals), while Inhibins are heterodimers of a unique α subunit and one of the β subunits.
- Activin A is a widely expressed homodimer of two βA chains.
- The βA subunit can also heterodimerize with a βB or βC subunit to form Activin AB and Activin AC, respectively.
- The 14 kDa mature human βA chain shares 100% amino acid sequence identity with bovine, feline, mouse, porcine, and rat βA.
仕様
- サイズ：100ug
- Source：ActiveMax Human Activin A, Tag Free, low endotoxin (ACA-H421b) is expressed from human 293 cells (HEK293). It contains AA Gly 311 - Ser 426 (Accession # AAH07858.1).
- Molecule：Activin A
- Synonyms：Activin A,INHBA
- Species：Human
- Tag：Tag Free
- Expression Systems：HEK293
- Expression Rigeion：Gly 311 - Ser 426
- Conjugate：Unconjugated
- Accession：AAH07858.1
- Molecular Weight：13.0 kDa
- Characteristics：This protein carries no "tag". The protein has a calculated MW of 13.0 kDa. As a result of glycosylation, the protein migrates as 14-15 kDa under reducing (R) condition, and 23-25 kDa under non-reducing (NR) condition (SDS-PAGE).
- Endotoxin Level：Less than 0.1 EU per ug by the LAL method.
- Purity：>95% as determined by SDS-PAGE.
- Buffer：30% ACN, 0.056% TFA
- Package Size：100ug*1
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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86-7922-34
ActiveMax Human Activin A / INHBA Protein, Tag Free, low endotoxin 25ug
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86-7922-35
ActiveMax Human Activin A / INHBA Protein, Tag Free, low endotoxin 100ug
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