Background：T-cell surface glycoprotein CD3 delta & CD3 gamma chain, also known as CD3D & CD3G or CD3D&CD3G respectively, are single-pass type I membrane proteins.
CD3D, together with CD3- epsilon(CD3E) , CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex.
T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.
仕様
サイズ：50ug
Source：Biotinylated Human CD3E&CD3G Heterodimer Protein, His,Avitag&Tag Free (CDG-H82W3) is expressed from human 293 cells (HEK293). It contains AA Asp 23 - Asp 126 (CD3E) & Gln 23 - Ser 116 (CD3G) (Accession # NP_000724.1 (CD3E) & AAI13831 (CD3G)).
Molecule：CD3E & CD3G
Synonyms：CD3 epsilon & CD3 gamma,CD3E & CD3G
Species：Human
Tag：His Tag & Avi Tag
Expression Systems：HEK293
Expression Rigeion：Asp 23 - Asp 126 (CD3E) & Gln 23 - Ser 116 (CD3G)
Conjugate：Precision Avi
Accession：NP_000724.1 (CD3E) & AAI13831 (CD3G)
Molecular Weight：18.6 kDa & 14.7 kDa
Characteristics：Biotinylated Human CD3E&CD3G Heterodimer Protein, His,Avitag&Tag Free is produced by co-expression of CD3E and CD3G, has a calculated MW of 18.6 kDa (CD3E) and 14.7 kDa (CD3G). Subunit CD3E is fused with a polyhistidine tag at the C-terminus, followed by an Avi tag and subunit CD3G contains no tag at the C-terminus. The reducing (R) heterodimer protein migrates as 22 kDa and 24-30 kDa due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
